Predictor | Univariate analysis | Multivariate analysis# | ||
HR (95% CI) | p-value | HR (95% CI) | p-value | |
Age per year | 1.06 (1.01–1.11) | 0.028 | NS | |
SaO2 nadir per % | 0.94 (0.89–0.99) | 0.029 | NS | |
Coronary artery disease | 3.50 (1.51–8.10) | 0.004 | 4.37 (1.81–10.6) | 0.001 |
PAD history ≥4 years | 3.32 (1.13–9.79) | 0.030 | 3.80 (1.26–11.5) | 0.018 |
HDL/cholesterol per % | 0.94 (0.90–0.99) | 0.021 | 0.95 (0.90–1.00) | 0.048 |
AHI ≥20 events·h−1 | 4.26 (1.66–10.9) | 0.003 | 5.13 (1.89–13.9) | 0.001 |
HR: hazard ratio; SaO2: arterial oxygen saturation; PAD: peripheral arterial disease; HDL/cholesterol: high-density lipoprotein/total cholesterol ratio; AHI: apnoea/hypopnoea index; NS: not selected into the final model. #: performed using stepwise selection method (inclusion criteria p<0.05 and exclusion criteria p≥0.05).