Outcome | Baseline | Change over 1 year | p-value |
Body mass index kg·m−2 | 26.4 (24.1–31.6) | 0.2 (−0.5–1.2) | <0.001 |
4MGS m·s−1 | 0.90±0.26) | −0.04±0.16) | <0.001 |
ISW m | 220 (100–340) | −30 (−70–20) | <0.001 |
ISW % predicted | 40 (20–57) | −5 (−10–3) | <0.001 |
MRC dyspnoea score | 3 (2–4) | 0 (−1–1) | 0.096 |
CAT score | 22 (16, 27) | 1 (−4, 4) | 0.745 |
SGRQ score | |||
Symptoms domain | 61.5 (21.8) | −2.2 (18.3) | 0.191 |
Activities domain | 68.7 (23.0) | −0.5 (15.7) | 0.710 |
Impacts domain | 36.7 (19.2) | −2.4 (13.6) | 0.057 |
Total score | 50.6 (18.4) | −1.7 (11.7) | 0.110 |
FEV1 % predicted | 46.1 (19.9) | 0.8 (31.6) | 0.840 |
Data expressed as median (interquartile range) or mean±sd, unless otherwise stated. n=162. 4MGS: 4-m gait speed; ISW: incremental shuttle walk; MRC: Medical Research Council; CAT: COPD Assessment Test; SGRQ: St George’s Respiratory Questionnaire; FEV1: forced expiratory volume in 1 s.