Table 3– Multivariate linear regression outcomes with dependent variable sputum NLRP3 gene expression
VariableCoefficientsep-value95% CI
Age0.0030.0040.436-0.005–0.012
Sex0.0310.1020.761-0.173–0.234
NOD2 mRNA0.1470.0215<0.0010.1040.190
Neutrophils ×104 per mL2.65×10−51.32×10−50.0499.80×10−75.30×10−5
IL-1β pg·mL−13.28×10−61.74×10−60.064-2.01×10−6–6.75×10−6
IL-8 ng·mL−1-0.0070.0030.039-0.013-0.3.5×10−4
Constant-0.2220.2990.459-0.819–0.375
  • NLRP: nucleotide-binding domain, leucine-rich repeat-containing family protein; NOD: nucleotide-binding oligomerisation domain-containing protein; IL: interleukin. Values in bold are statistically significant.