Table 3– Lung function tests compared between groups
BPDNon-BPDFull-termBPD versus non-BPDBPD versus non-BPD#BPD versus full-termNon-BPD versus full-term
Subjects n564055
FEV1 z-score-1.41±1.25-0.19±1.160.14±0.96-1.22 (-1.72− -0.72)***-1.83 (-2.76− -0.90)***-1.55 (-1.97− -1.13)***-0.33 (-0.76–0.11)
FEV1 % pred81.89±15.9096.98±15.22101.16±11.40-15.08 (-21.50− -8.66)***-22.63 (-34.34− -10.91)***-19.27 (-24.48− -14.06)***-4.19 (-9.61–1.23)
FVC z-score-0.79±1.140.17±0.980.12±0.94-0.96 (-1.40− -0.52)***-1.53 (-2.22− -0.84)***-0.91 (-1.30− -0.52)***0.05 (-0.35–0.44)
FVC % pred90.11±14.46101.85±12.60101.67±0.83-11.74 (-17.38− -6.10)***-19.25 (-27.99− -10.50)***-11.57 (-16.38− -6.75)***0.18 (-4.61–4.97)
FEV1/FVC z-score-0.68±0.22-0.13±1.220.34±0.89-0.55 (-1.16− -0.06)-0.36 (-1.51–0.79)-1.02 (-1.52− -0.53)*-0.47 (-0.90− -0.40)*
FEV1/FVC % pred94.32±13.4198.45±10.32102.67±7.18-4.13 (-9.15–0.89)-3.00 (-12.56–6.56)-8.35 (-12.41− -4.29)*-4.22 (-7.79− -0.66)*
FEF25–75% z-score-1.80±1.10-1.13±1.02-0.56±1.45-0.67 (-1.11–0.23)**-0.90 (-1.72–0.26)**-1.24 (-1.73− -0.769)***-0.57 (-1.10− -0.43)*
FEF25–75% % pred61.63±23.5974.93±22.0690.96±21.55-13.30 (-22.74− -3.86)**-20.99 (-36.78− -5.40)**-29.34 (-37.84− -20.84)***-16.04 (-25.02− -7.06)***
  • Data are presented as mean±sd or unadjusted mean difference (95% CI), unless otherwise stated. BPD: bronchopulmonary dysplasia; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF25–75%: forced expiratory flow at 25–75% of FVC. #: adjusted for maternal smoking, having ever smoked, birth weight and gestational age. *: p<0.05; **: p<0.01; ***: p<0.001.