Table 2– Main indications for bronchoscopy per randomisation group
Indication for bronchoscopyBolusInfusionTotalp-value
Subjects n355347702
Suspicion of malignancy83 (23.4)93 (26.8)176 (25.1)0.296
Interstitial lung disease29 (8.2)48 (13.8)77 (10.7)0.016
Infection130 (36.6)107 (30.8)237 (33.8)0.105
Chronic cough17 (4.8)9 (2.6)26 (3.7)0.124
Haemoptysis5 (1.4)10 (2.9)15 (2.1)0.201
Bronchial toilette35 (9.9)35 (10.1)70 (10.0)0.920
Stenting10 (2.8)9 (2.6)19 (2.7)0.855
Laser therapy5 (1.4)3 (0.9)8 (1.1)0.725
Miscellaneous41 (11.5)32 (9.2)73 (10.4)0.312
Diagnostic procedures
 Inspection only23 (6.5)23 (6.6)46 (6.6)1.000
 Bronchial washings99 (28.0)83 (23.9)182 (26.0)0.222
 BAL214 (60.3)212 (61.3)426 (60.8)0.788
 Bronchial brushing40 (11.3)46 (13.3)86 (12.3)0.430
 Endobronchial biopsy48 (13.5)56 (16.1)104 (14.8)0.329
 Transbronchial biopsy48 (13.5)72 (20.7)120 (17.1)0.011
 Mediastinal TBNA24 (6.8)36 (10.4)60 (8.5)0.087
 Peripheral TBNA15 (4.2)20 (5.8)35 (5.0)0.349
 EBUS24 (6.8)29 (8.4)53 (7.5)0.423
Interventions
 Laser therapy6 (1.7)7 (2)13 (1.9)0.748
 Stenting12 (3.4)12 (3.5)24 (3.4)0.955
 Calypso implantation2 (0.6)2 (0.6)4 (0.6)0.982
 Valve implantation3 (0.8)4 (1.2)7 (1.0)0.682
Number of procedures
 1203 (57.5)174 (50.3)377 (53.9)
 279 (22.4)82 (23.7)161 (23.0)0.115
 ≥348 (13.6)67 (19.4)115 (16.5)
  • Data are presented as n (%), unless otherwise stated. BAL: bronchoalveolar lavage; TBNA: transbronchial needle aspiration; EBUS: endobronchial ultrasound.