New-onset asthma subjects without asthma at ECRHS I | New-onset nasal allergy subjects without nasal allergy at ECRHS I | |
Subjects n | 874 | 754 |
Sex | ||
Female | 1.79 (1.02–3.15) | 1.44 (0.88–2.35) |
Male | 1 | 1 |
Centre | ||
Erfurt | 0.75 (0.44–1.28) | 0.76 (0.47–1.24) |
Hamburg | 1 | 1 |
Asthma at baseline | 1.75 (0.59–5.16) | |
No asthma at baseline | 1 | |
Nasal allergy at baseline | 2.51 (1.43–4.42) | |
No nasal allergy at baseline | 1 | |
Eczema at baseline | 1.62 (0.95–2.78) | 1.76 (1.09–2.86) |
No eczema at baseline | 1 | 1 |
BHR at baseline | 4.14 (2.29–7.48) | 1.69 (0.96–2.99) |
No BHR at baseline | 1 | 1 |
Family history# | ||
Negative | 1 | 1 |
Positive | 1.32 (0.74–2.34) | 1.29 (0.75–2.07) |
Social status¶ | ||
≤16 years | 1 | 1 |
17–23 years | 0.33 (0.11–0.98) | 1.23 (0.18–8.37) |
>23 years | 0.19 (0.05–0.69) | 1.20 (0.17–8.60) |
Pet ownership at baseline | 0.91 (0.50–1.66) | 0.85 (0.49–1.47) |
No pet ownership at baseline | 1 | 1 |
Mould exposure ever | 0.77 (0.38–1.57) | 1.49 (0.88–2.52) |
No mould exposure ever | 1 | 1 |
Job exposure+ ever | 1.05 (0.61–1.80) | 0.89 (0.54–1.47) |
No job exposure ever | 1 | 1 |
Current smoking at baseline | 0.71 (0.39–1.27) | 0.63 (0.37–1.07) |
No current smoking at baseline | 1 | 1 |
Any positive SPT§ | 2.51 (1.46–4.29) | 3.42 (2.12–5.52) |
No positive SPT | 1 | 1 |
Any positive RASTƒ | 1.98 (1.16–3.39) | 2.66 (1.65–4.31) |
No positive RAST | 1 | 1 |
Contact with older children in early life | 0.87 (0.47–1.60) | 0.72 (0.42–1.09) |
No contact with older children in early life | 1 | 1 |
Data are presented as relative risk (95% CI), unless otherwise stated. ECRHS: European Community Respiratory Health Survey; BHR: bronchial hyperresponsiveness; SPT: skin prick test; RAST: radioallergosorbent test. #: parental history of asthma, nasal or skin allergy, or eczema; ¶: age at the end of full-time education; +: exposed to vapours, gas, dust or fumes in a job; §: at least one positive SPT; ƒ: at least one positive RAST.