1st evaluation | 2nd evaluation | Change between the 1st and the 2nd evaluation | P | |
---|---|---|---|---|
Spirometry (Z score) | ||||
FVC | –0.125 | –0.420 | –0.380 | 0.64 |
FEV1 | –1.005 | –1.380 | 0 | 0.87 |
FEV1/FVC | –1.570 | –1.44 | –0.065 | 0.97 |
FEF25–75 | –2.150 | –2.090 | 0 | 0.51 |
HRCT scores (%) | ||||
Bronchiectasis | 8.3 | 17 | 9.5 | 0.001 |
Mucus plugging | 5.6 | 25 | 16.6 | 0.004 |
Peribronchial thickening | 9.3 | 15 | 2.7 | <0.001 |
Parenchyma | 5.6 | 7.4 | 1.8 | 0.003 |
Mosaic perfusion pattern | 0 | 10 | 0 | 0.009 |
Total | 7.7 | 17.4 | 7.2 | 0.001 |
Data presented as median values.