Table 1– Values at baseline and at follow-up after 3 months of noninvasive positive-pressure ventilation
Method/parameterBaselineFollow-upp-value
Subjects nMean±sdSubjects nMean±sd
BMI1836.1±9.81835.1±90.14
Mean body weight kg18104±3018102±270.14
Right heart catheterisation
 sPAP mmHg1771 ±181644±130.001
 mPAP mmHg1749±131631±9<0.001
 dPAP mmHg1735±101623±70.001
 PAWP mmHg1711±4169±50.167
 dPVG mmHg1723±101614±4<0.001
 PVR dyn·s·cm−517499±17116292±108<0.001
 Cardiac index L·min−1·m−2173.2±0.7153.2±0.70.807
 RAP mmHg1714±8158±3<0.01
6-min walking distance m17303±13316384±126<0.01
Echocardiography
 EF %1867±111867±90.931
 E/E′1710±4178.5±20.124
 LA volume mL1857±331877±450.002
 RA area cm21825.0±7.91819.5±5.90.002
 TAPSE mm1818±51825±4<0.001
Daytime blood gases
 PO2 at rest mmHg1756.4±14.41671.2±11.30.01
 PCO2 at rest mmHg1752.2±5.81644.5±4<0.001
 SpO2 at rest %1787±71694±3<0.01
Night-time oximetry and capnometry
 Mean night-time CO2 mmHg1761.8±7.71446.4±90.001
 Maximum night-time CO2 mmHg1772.7±10.61354.7±7.40.002
 Mean night-time SpO2 %1882±101694±30.001
Cardiopulmonary exercise test
 Maximum work rate W967±40985±320.028
 V′O2 peak % predicted965±25971±230.24
NT-proBNP pg·mL−1142403±208213377±4160.001

  • Only the patients with data available at both baseline and 3 month follow-up were considered for analysing mean changes in each parameter. BMI: body mass index; sPAP: systolic pulmonary arterial pressure (PAP); mPAP: mean PAP; dPAP: diastolic PAP; PAWP: pulmonary artery wedge pressure; dPVG: diastolic pulmonary vascular gradient; PVR: pulmonary vascular resistance; RAP: right atrial pressure; EF: ejection fraction; E/E′: early transmitral filling (E) to early diastolic mitral annular velocity (E′) ratio; LA: left atrial; RA: right atrial; TAPSE: tricuspid annular plane systolic excursion; PO2: oxygen tension; PCO2: carbon dioxide tension; SpO2: arterial oxygen saturation measured by pulse oximetry; V′O2: oxygen uptake; NT-proBNP: N-terminal pro-brain natriuretic peptide.