| Variables (units) | Sea level | Altitude Day 2 & 3 | Placebo | Sildenafil | Sildenafil + Sixtasentan |
|---|---|---|---|---|---|
| DmCO/VA | 102.3 (9.8) | 107.9 (9.7)* | 106,8 (20,9) | 104,6 (20,5) | 109,8 (21,5) |
| Vc corr/VA | 100.1 (12.3) | 131.8 (20.3)* | 115,7 (22,7) | 111,8 (21,9) | 120 (23,5) |
Data are presented as mean (sd). VA: alveolar volume. No statistically significant difference at 5% between groups was observed UNDER TRIAL. *Statistically difference at 5% vs SEA.