Primary and secondary outcomes
| Outcome | Treatment A | Treatment B | Difference between proportions (A – B) (95% CI) | p value |
|---|---|---|---|---|
| Mean ASS T60 (SD) | 4.72 (1.38) | 4.95 (1.41) | –0.27 (–0.50, –0.03) | 0.03 |
| Mean (SD) LOS (hours) | 32 (25) | 35 (27) | –2.94 (–7.52, 1.64) | 0.20 |
| Need for IV treatment (%) | 24/250 (10) | 29/251 (12) | –0.02 (–0.08, 0.04) | 0.57 |
| Additional salbutamol doses (IQR) | 8 (2–13) | 8 (3–14) | 0.00 (–1, 1) | 0.35 |
| n=248 | n=250 | |||
| PICU/intubation (%) | 18/243 (7) | 7/252 (3) | 0.05 (0.00, 0.10) | 0.03 |
| Step down to spacer treatment at one hour (%) | 203/248 (82) | 205/250 (82) | 0.00 (–0.07, 0.07) | 0.94 |
| n=250 | n=250 |