Table 2– Elements that favour observation, tailored options or standard management for patients with putative slow-growing lung cancer
ObservationTailored optionsStandard management
AgeRelatively old#Relatively old#Relatively young#
Comorbidity burdenHighHighLow
DetectionScreening or incidental CT findingScreening or incidental CT findingClinically detected
SizeRelatively smallRelatively smallRelatively large
MorphologyNonsolidPart-solidSolid
VDTNo progression or long VDT#No progression or long VDT#Relatively short VDT#
PET/SUVPET-negative or low SUV#PET-negative or low SUV#PET-positive, high SUV#
Surgical optionsUnsuitable for sublobar resectionSuitable for sublobar resectionSuitable for VATS lobectomy
Nonsurgical optionsSBRT or RFA available
Psychological profileComfortable with being followedAnxious, prefers certaintyAnxious, prefers certainty
  • VDT: volume doubling time; PET: positron emission tomography; SUV: standardised uptake value; CT: computed tomography; SBRT: stereotactic body radiation therapy; RFA: radiofrequency ablation; VATS: video-assisted thoracoscopy. #: no conventional limit.