Table 3– Change from baseline up to month 12 in composite physiologic index (CPI)
Macitentan 10 mgPlacebo
Subjects n115#58#
CPI
 Baseline46.5 (1.3–73.7)48.3 (17.4–70.5)
 Up to month 1250.7 (-9.2–80.9)55.1 (17.5–80.9)
 Change from baseline3.7 (-16.7–49.5)4.2 (-6.7–41.1)

  • Data are presented as median (range), unless otherwise stated. #: data from subjects in the all-treated set who had a valid baseline measure of CPI.