Table 3– Correlation between high-resolution computed tomography (HRCT) score and impedance–pH findings (acid exposure time and impedance-detected reflux episodes) with the presence/concentration of pepsin and bile acids in saliva and bronchoalveolar lavage fluid (BALF) in idiopathic pulmonary fibrosis patients
HRCT scoreAcid exposure timeTotal number of reflux episodes
r2p-valuer2p-valuer2p-value
Presence of pepsin in saliva0.5260<0.0010.21930.0030.4007<0.001
Presence of bile acids in saliva0.4269<0.0010.14930.0170.52640.001
Concentration of bile acids in saliva0.25910.0130.01290.6060.07120.218
Presence of pepsin in BALF0.6033<0.0010.23440.0260.28450.013
Presence of bile acids in BALF0.46050.0010.36600.0040.45660.001
Concentration of bile acids in BALF0.38430.0240.04270.4980.35580.031