Table 6– Ratio of protein unbound (free (f)) area under the concentration–time curve from 0 to 24 h post-dosage (AUC_0–24) relative to the minimum inhibitory concentration (MIC) of sulfamethoxazole (SMX) after receiving 480 mg and 960 mg of co-trimoxazole^#

Patient	MIC mg·L⁻¹	SMX 400 mg		SMX 800 mg
Patient	MIC mg·L⁻¹	AUC_0–24 mg·h·L⁻¹	fAUC_0–24 /MIC	AUC_0–24 mg·h·L⁻¹	fAUC_0–24 /MIC
1	25	376	3	774	7
2	4.75	297	14
5	9.5	658	16	991	24
6	25	509	5
7	4.75	597	29
8	4.75	367	18
9	19	752	9
10	4.75	281	14

Data are presented as n. ^#: n = 8.