Table 4– Pharmacokinetic parameters of 400 mg sulfamethoxazole (SMX) at steady state after oral administration of 480 mg of co-trimoxazole#
AUC0–24 mg·h·L−1371.5 (360–574.8)
Clearance mL·min−1·kg−10.19 (0.14–0.25)
V D L·kg−10.15 (0.13–0.22)
t ½ h10.1 (8.7–10.8)

  • Data are presented as median (interquartile range). AUC0–24: area under the concentration–time curve up to 24 h post-dosage; VD: volume of distribution; t½: half-life. #: n = 8.