Table 1– Demographic data according to lower respiratory tract infection (LRTI) status
No LRTIRV LRTIRSV LRTIRV/RSV LRTIOverall p-value
Subjects74201712
Gestational age weeks34.1 (25.7–35.9)32.9 (27.4–35.7)32.6 (28.9–35.6)32.1 (23.0–35.9)0.044
Birthweight g2070 (895–3610)1558 (670–2512)1756 (1080–2650)1595 (610–2546)0.002
Males39 (53)9 (45)9 (53)5 (42)0.85
Ethnicity0.043
 Caucasian28 (38)2 (10)3 (18)2 (17)
 Black Caribbean19 (26)2 (10)5 (29)2 (17)
 Black African12 (16)4 (20)5 (29)2 (17)
 Asian3 (4)2 (10)1 (6)0 (0)
 Hispanic1 (1)0 (0)0 (0)1 (8)
 Mixed race11 (15)10 (50)3 (18)5 (41)
Antenatal smoking#11 (15)4 (20)2 (12)2 (17)0.91
Antenatal steroids40 (54)16 (80)16 (94)8 (67)0.014
Surfactant11 (15)7 (35)1 (6)6 (50)0.005
Duration of ventilation days0 (0–82)1 (0–103)1 (0–17)1.5 (0–81)0.39
Bronchopulmonary dysplasia4 (5)5 (25)0 (0)3 (25)0.008
Family history of atopy52 (70)13 (65)8 (47)7 (58)0.32
Breastfeeding62 (84)15 (75)11 (65)8 (67)0.20
Eczema20 (28)3 (16)2 (12)2 (17)0.45
Daycare attendance2 (3)0 (0)1 (6)1 (8)0.52
Number of siblings1 (0–5)1 (0–5)1 (0–4)1 (0–4)0.91
Palivizumab0 (0)3 (15)0 (0)1 (8)0.005
  • Data are presented as n, median (range) or n (%), unless otherwise stated. RV: rhinovirus; RSV: respiratory syncytial virus. #: all mothers who smoked antenatally also smoked postnatally; : a family history of atopy was defined as a first degree relative (parent or sibling) with asthma, eczema, hay fever or an allergy.