Table 4– Predictors of mortality in the total chronic obstructive pulmonary disease population, according to the multivariate Cox regression analysis
HR (95% CI)p-value
Age years1.030 (1.004–1.056)0.021
PaO2 kPa0.851 (0.748–0.969)0.015
TLCO % pred0.971 (0.957–0.984)<0.001
FEV1 % pred1.016 (0.974–1.060)0.463
FVC % pred0.977 (0.950–1.004)0.090
FEV1/FVC0.988 (0.944–1.033)0.582
RV % pred0.987 (0.975–1.001)0.055
FRC % pred1.021 (0.998–1.045)0.078
TLC % pred1.011 (0.979–1.044)0.507
IC/TLC %2.009 (0.378–3.451)0.628
PaCO2 kPa0.991 (0.798–1.230)0.932
BMI kg·m−21.006 (0.973–1.041)0.710

  • Carbon monoxide transfer factor (TLCO) % pred and forced expiratory volume in 1 s (FEV1) % pred entered the analysis as continuous variables. PaO2: arterial oxygen partial pressure; FVC: forced vital capacity; RV: residual volume; FRC: functional residual capacity; TLC: total lung capacity; IC: inspiratory capacity; PaCO2: arterial carbon dioxide partial pressure; BMI: body mass index.