XDR alone | XDR+2sli | XDR+sliG4 | XDR+sliG4EZ | |
Subjects n | 301 | 68 | 48 | 42 |
Number of drugs to which the strain was resistant# | ||||
5 | 9 | 0 | 10 | 0 |
6 | 31 | 4 | 27 | 29 |
7 | 31 | 13 | 8 | 10 |
8 | 18 | 31 | 6 | 7 |
9 | 10 | 25 | 4 | 5 |
10 | 1 | 21 | 35 | 40 |
11 | 0 | 6 | 8 | 10 |
Data are presented as %, unless otherwise stated. Column totals may exceed 100% due to rounding. XDR alone: resistance to isoniazid and rifampicin, plus any fluoroquinolone and any second-line injectable drug (sli); XDR+2sli: XDR-TB, plus resistance to both an aminoglycoside injectable (kanamycin/amikacin) and to capreomycin; XDR+sliG4: XDR-TB, plus resistance to all second-line TB drugs tested, with, as a minimum, resistance to kanamycin and to at least one group 4 (G4) drug; XDR+sliG4EZ: XDR-TB, plus resistance to all first- and second-line TB drugs tested, with, as a minimum resistance to kanamycin, one group 4 drug and either pyrazinamide (Z) and/or ethambutol (E). #: the number of drugs includes isoniazid, rifampicin and at least one fluoroquinolone and one second-line injectable, so all patients were resistant to at least one drug in addition to these four.