Table 2– Criteria for exclusion of patients for outpatient treatment

First author [Ref.]	Extra risk tools	Haemodynamically unstable	Respiratory unstable	i.v. pain medication	Bleeding risk	Therapeutic OAT	Comorbidities	Social	Pregnant	Renal impairment	Contraindications LMWH
Agterof [4]	NT-proBNP >500 ng·mL⁻¹	X	X	X	X	X	X	X	X	X
Aujesky [5]	PES index >85 [16]	X	X	X	X			X	X	X	X
Beer [20]		X			X	X		X		X	X
Davies [21]			X	X	X	X	X	X	X
Erkens [6]		X	X		X		X			X
Kovacs [22]		X	X	X	X		X	X
Kovacs [7]		X	X	X	X
Lui [23]	Massive PE	X	X		X			X			X
Olsson [24]	Large PE (affecting >40% lung perfusion on V′/Q′ scan)			X	X		X
Ong [25]		X	X	X	X		X	X
Otero [26]	Clinical score >2, troponin T >0.1 ng·mL⁻¹, RVD on TTE	X	X		X		X		X
Rodriguez-Cerrillo [27]	Massive PE (two or more lobar branches)	X	X		X		X	X		X	X
Siragusa [28]				X	X		X	X		X
Wells [29]		X	X	X	X	X	X	X		X	X
Zondag [8]		X	X	X	X	X	X	X	X	X	X

OAT: oral anticoagulant therapy; LMWH: low molecular weight heparin; NT-proBNP: N-terminal pro-brain natriuretic peptide; PES: pulmonary embolism severity; PE: pulmonary embolism; V′/Q′: ventilation/perfusion ratio; RVD: right ventricular dysfunction; TTE: transthoracic echocardiography.