| A patient admitted as a clinical case of COPD exacerbation that is later judged to have another primary diagnostic reason for admission, e.g. the subsequent diagnosis is changed from COPD to heart failure |
| Any other primary cause of deterioration and hospital admission, such as: |
| Pneumonia |
| Pulmonary embolism |
| Pulmonary oedema |
| Pneumothorax |
| Thoracic trauma |
| Pleural effusion |
| Asthma |
| Pulmonary fibrosis |
| Sleep apnoea with no treatment |
| Kyphoscoliosis |
| Obesity-hypoventilation syndrome |
| Neuromuscular pathology |
| Tracheal or upper airway stenosis |
| Severe bronchiectasis |
| Severe tuberculosis sequelae |
| Bronchogenic carcinoma or any other thoracic neoplasm |
| Extrapulmonary diseases as the primary diagnosis for admission that may produce similar symptoms, such as: |
| Extensive cancer |
| Hepatic insufficiency |
| Renal insufficiency |
| Cardiac failure |
| Any other condition as judged by the investigator |
COPD: chronic obstructive pulmonary disease.