Table 1– Characteristics of all eligible study patients
Patients with complete follow-upAll other eligible patientsp-value
Subjects n9344
Male56 (61)26 (60)0.90
Age yrs4.5 (2.2–6.8)4.6 (2.1–6.9)0.67
Duration of outpatient clinic asthma care before study months17 (8–27)17 (9–28)0.58
Maintenance medication
 ICS86 (92)42 (95)0.51
 ICS and long-acting bronchodilators7 (8)2 (5)0.51
 ICS (fluticasone) dose μg250 (125–500)250 (125–500)0.73
Scheduled visits to outpatient clinic in yr before study5 (4–6)4 (2–5)0.007
Hospitalisations in yr before study0 (0–5)0 (0–1)0.07
ACQ baseline (<0.75=well controlled, >1.5=not well controlled)0.5 (0.2–1.3)NANA
PACQoL baseline (score 1–7; 1=low, 7=high)6.2 (5.3–6.8)NANA
Smoking parent(s)28 (30)NANA
Educational level of mother (1=low, 7=high)5 (4–7)NANA
Positive specific IgE to common inhalant allergens43 (50)24 (65)+<0.001
FEV1 baseline#0.66±1.1NANA
FVC baseline#0.29±1.3NANA
Rrs,int baseline#1.90±2.8NANA
  • Data are presented as n (%), median (interquartile range) or mean±sd, unless otherwise specified. ICS: inhaled corticosteroids; ACQ: Asthma Control Questionnaire [20]; PACQoL: Paediatric Asthma Caregiver Quality of Life Questionnaire; Ig: immunoglobin; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; Rrs,int: resistance of respiratory system measured by the interrupter technique; NA: not available. #: z-score, n=33; : n=86; +: n=37.