Table 3 Domestic cleaning exposure and asthma phenotypes

	Subjects n	Self-reported exposure			Principal component analysis
		Home cleaning	Spray use (≥1 day per week)		Factor 1 “essential tasks”		Factor 2 “domestic wizard”		Factor 3 “chemical products”
		≥1 day per week	1 type of spray	≥2 types of sprays	2nd tertile	3rd tertile	2nd tertile	3rd tertile	2nd tertile	3rd tertile
Symptom score
0	284	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
1	171	1.17 (0.73–1.88)	0.93 (0.59–1.47)	0.99 (0.56–1.73)	1.32 (0.78–2.26)	1.45 (0.85–2.48)	0.89 (0.54–1.47)	0.85 (0.50–1.44)	0.89 (0.53–1.49)	0.97 (0.58–1.62)
		1.17 (0.73–1.88)	0.93 (0.59–1.47)	0.99 (0.56–1.73)	1.32 (0.78–2.26)	1.45 (0.85–2.48)	0.89 (0.54–1.47)	0.85 (0.50–1.44)	0.89 (0.53–1.49)	0.97 (0.58–1.62)
≥2	228	1.85 (1.16–2.94)	0.92 (0.59–1.45)	2.50 (1.54–4.03)	1.68 (1.02–2.76)	1.57 (0.93–2.64)^#	0.75 (0.46–1.22)	1.21 (0.75–1.96)	0.90 (0.56–1.45)	0.97 (0.59–1.59)
		1.85 (1.16–2.94)	0.92 (0.59–1.45)	2.50 (1.54–4.03)	1.68 (1.02–2.76)	1.57 (0.93–2.64)^#	0.75 (0.46–1.22)	1.21 (0.75–1.96)	0.90 (0.56–1.45)	0.97 (0.59–1.59)
Current asthma
Never	439	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
All	244	1.34 (0.87–2.05)	0.68 (0.44–1.04)^¶	1.67 (1.08–2.56)	1.42 (0.92–2.20)	1.27 (0.78–2.06)	0.61 (0.39–0.97)	1.17 (0.76–1.81)	0.97 (0.64–1.46)	0.84 (0.54–1.30)
		1.34 (0.87–2.05)	0.68 (0.44–1.04)^¶	1.67 (1.08–2.56)	1.42 (0.92–2.20)	1.27 (0.78–2.06)	0.61 (0.39–0.97)	1.17 (0.76–1.81)	0.97 (0.64–1.46)	0.84 (0.54–1.30)
Controlled	99	1.12 (0.66–1.90)	0.67 (0.38–1.18)	1.32 (0.75–2.34)	0.78 (0.42–1.46)	1.24 (0.66–2.30)	0.52 (0.28–0.97)	1.04 (0.54–1.84)	0.85 (0.47–1.52)	0.87 (0.48–1.59)
		1.12 (0.66–1.90)	0.67 (0.38–1.18)	1.32 (0.75–2.34)	0.78 (0.42–1.46)	1.24 (0.66–2.30)	0.52 (0.28–0.97)	1.04 (0.54–1.84)	0.85 (0.47–1.52)	0.87 (0.48–1.59)
Poorly controlled	128	1.50 (0.88–2.52)	0.65 (0.38–1.12)	2.04 (1.25–3.32)	2.06 (1.19–3.54)	1.25 (0.69–2.26)	0.72 (0.42–1.25)	1.36 (0.81–2.28)	1.08 (0.64–1.82)	0.84 (0.48–1.45)
		1.50 (0.88–2.52)	0.65 (0.38–1.12)	2.04 (1.25–3.32)	2.06 (1.19–3.54)	1.25 (0.69–2.26)	0.72 (0.42–1.25)	1.36 (0.81–2.28)	1.08 (0.64–1.82)	0.84 (0.48–1.45)

Data are presented as OR (95% CI), unless otherwise stated. Significant associations are presented in bold. Odds ratios were adjusted for age, smoking habits, body mass index and occupational exposure. Principal component analysis evidenced three domestic exposure patterns for the females (see online supplementary table E1) labelled “essential tasks” (factor 1), “domestic wizard” (factor 2) and “chemical products” (factor 3). In females with current asthma, there were 17 missing values for asthma control. ^#: p=0.09; ^¶: p=0.07.