Data are presented as n (%), unless otherwise specified. For each parameter, changes of ≥10% in forced expiratory volume in 1 s (FEV₁) or forced vital capacity (FVC) or of ≥15% in diffusing capacity of the lung for carbon monoxide (D_L,CO) constituted improvement or deterioration. The overall lung function outcome was defined based on increases or decreases of ≥10% in FEV₁ and/or FVC and/or of ≥15% in D_L,CO. In case of discrepancies, the impaired parameter was used. The patients whose lung function was stable (neither improved nor deteriorated) are not shown. The estimated cumulative incidences of deterioration in lung function parameters at 5 yrs were calculated considering the competing risks framework for overall lung function and according to each lung function parameter. ^#: serial D_L,CO results were available for 40 patients.