Table 3– Observational and randomised computed tomography screenings for lung cancer, study designs and results, continued
No.Median follow-upMales %Age yrsExposure (smoking status)Ratio of COPDPositive screening for nodulesLung cancerStage ILung cancer operabilityMortalityLung cancer mortality
1NR9060.4 (38–83)NRNR20.30%15 (0.3%)14 (93%)14 (93%)NRNR
2NR5467Current 100%NR0.2333 (3.3%)28 (84.8%)NRNRNR
3NR4665Current 54.3%NR5.1% (1996)60 (0.4%)55 (92%)60 (100%)5 (0.1%)2 (0.04%)
4.0% (1997)
3.5% (1998)
4NR9863 (38–81)Current 97%NR18.4%5 (0.8%)2 (40%)1 (20%)NR4 (0.7%)
5NR8864Current 61%NR11.5% (initial)14 (0.9% initial)11 (78.6% initial)12 (86% initial)8 (0.5%)3 (0.2%)
Former 25%9.1% (repeated)22 (0.3% repeated)18 (82% repeated)17 (77% repeated)
6NR7253 (40–78)Current 100%NR43%11 (1.3%)7/12 lesions (58%)7/12 lesions (58%)4 (0.5%)2 (0.2%)
7NR79NRCurrent 62.1%NR26.4% (initial)40 (0.5%)35 (87.5%)40 (100%)NRNR
8NR7158 (50–84)Current 86%NR29%22 (2.1%)17 (77%)21 (95%)8 (0.8%)1 (0.1%)
95 yrs5259 (50–85)Current 61%NR51% (initial), 74% (total)66 (4.3%)17/28 subsequent NSCLC cases (61%)NR48 (3.2%)9 (0.6%)
10NR59NRCurrent 58%NR34.5%40 (2.4%)19 (48%)NRNRNR
NR15.8%20 (1.2%)8 (40%)NRNRNR
11NR7156 (47–75)Current 65.0%NR45.2%8 (2.1%)3 (37.5%)NRNRNR
56 (47–76)Current 64.0%NR7.4%1 (0.8%)1 (100%)
1233.7 (1.8–79.2) months10064.3Current 56.0%446 (35%)#27.5%60 (4.7%)33 (55%)39 (65%)46 (3.6%)20 (1.6%)
64.6Current 56.9%370 (30.1%)#8.9%34 (2.8%)12 (35%)17 (50%)45 (3.8%)20 (1.7%)
p=0.04p=0.016p=0.004p=0.25p=0.83p=0.84
13NRNRNRNRNRNRNRNRNRNRNR
14NR5961.4Current 48%4674 (17.5%)NRNRNRNRNR354 (1.3%)
4652 (17.4%)442 (1.7%)
1540 (1–123) monthsNR61 (40–85)Current or former 82.8%NRNR484412 (85%)411 (85%)NR75
  • Follow-up period data are provided with ranges where possible. Age data are presented as mean or median and range. COPD: chronic obstructive pulmonary disease; NR: not reported; NSCLC: nonsmall-cell lung cancer. #: chronic respiratory symptoms (DANTE trial).