Characteristics | Nonhyperinflators | Hyperinflators |
Subjects (male/female) n | 65 (44/21) | 65 (44/21) |
Age yrs | 60±7 | 62±7 |
Height cm | 171±8 | 170±9 |
Mass kg | 73.5±18.4 | 74.6±15.6 |
BMI kg·m−2 | 25.1±5.6 | 25.7±4.2 |
Smoking history pack-yrs | 48.1±23.5 | 48.9±25.3 |
Duration of COPD yrs | 9.8±8.0 | 7.8±6.4 |
FEV1 L | 1.41±0.45 | 1.38±0.47 |
FEV1 % pred | 50±14 | 50±13 |
FVC L | 2.78±0.79 | 2.96±0.79 |
FVC % pred | 70±16 | 76±15* |
FEV1/FVC % | 51.1±10.9 | 46.7±11.1* |
FEV1/FVC % pred | 71±16 | 66±15.3* |
FEF25–75% L·s−1 | 0.61±0.37 | 0.52±0.29 |
FEF25–75% % pred | 21±12 | 18±9 |
IC L | 2.16±0.62 | 2.22±0.68 |
IC % pred | 75±18 | 78±20 |
IC/TLC | 30.6±7.5 | 29.9±7.6 |
TLC L | 7.08±1.17 | 7.50±1.52# |
TLC % pred | 115±15 | 122±16* |
FRC L | 4.92±1.00 | 5.27±1.28# |
FRC % pred | 151±30 | 161±33¶ |
RV L | 4.12±1.00 | 4.29±1.20 |
RV % pred | 196±48 | 201±49 |
Raw cmH2O·L−1·s−1 | 5.58±2.72 | 5.46±2.04 |
Raw % pred | 425±215 | 413±155 |
Wpeak W | 81±28 | 86±32 |
Wpeak % pred | 55±20 | 58±17 |
V′O2,peak L·min−1 | 1.25±0.41 | 1.27±0.47 |
V′O2,peak mL·kg−1·min−1 | 17.2±4.9 | 16.9±4.8 |
V′O2,peak % pred | 65±23 | 67±18 |
Data are presented as mean±sd, unless otherwise stated. BMI: body mass index; COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; FEF25–75%: forced expiratory flow at 25–75% of FVC; IC: inspiratory capacity; TLC: total lung capacity; FRC: functional residual capacity; RV: residual volume; Raw: airway resistance; Wpeak: peak incremental cycle work rate; V′O2,peak: peak oxygen uptake. *: p<0.05; #: p=0.08; ¶: p=0.05, all p-values between groups.