Smear microscopy alone | Xpert MTB/RIF alone | Smear microscopy followed by: | CXR followed by: | |||
Xpert MTB/RIF (if smear negative) | CXR (if smear negative), followed by Xpert MTB/RIF (if CXR suggestive of active TB) | Xpert MTB/RIF (if CXR suggestive of active TB) | Smear microscopy (if CXR suggestive of active TB), followed by Xpert MTB/RIF (if smear negative) | |||
Total test cost $ | 7420.00 | 21389.75 | 24130.74 | 32471.71 | 35746.74 | 36778.00 |
Incremental cost versus smear microscopy alone $ | 13969.75 | 16710.74 | 25051.71 | 28326.74 | 29358.00 | |
Number of correctly diagnosed non-TB cases | 683.33 | 658.33 | 654.17 | 648.15 | 651.23 | 648.15 |
Number of correctly diagnosed TB cases | 212.50 | 239.58 | 254.17 | 271.60 | 253.09 | 271.60 |
Additional number of TB cases correctly diagnosed versus smear microscopy alone | 27.08 | 41.67 | 59.10 | 40.59 | 59.10 | |
Cost per TB case detected (compared to smear microscopy) $ | 515.81 | 401.06 | 423.85 | 697.94 | 496.71 |
CXR: chest radiograph; TB: tuberculosis. #: similar tables stratified by HIV status can be found in the supplementary material (tables S6 and S7).