Table 4– Levels of biomarkers according to short-, mid- and long-term mortality
MortalityPatients nBiomarker
CRP mg·L−1WBCs ×103 cells·μL−1PCT ng·mL−1MR-proADM nmol·L−1
30-day224
 Survivors211156.4 (89.0–286.9)11.85 (8.4–16.83)0.41 (0.09–3.50)0.856 (0.592–1.911)
 Deaths13238.3 (123.4–332.5)14.7 (6.5–17.8)1.174 (0.477–6.69)2.341 (1.188–4.226)
 p-value0.2620.9140.123<0.0001
90-day220
 Survivors200155.8 (89.1–287.3)11.9 (8.4–16.6)0.376 (0.09–3.53)0.839 (0.578–1.158)
 Deaths20228.9 (77.6–283.0)10.5 (8.0–17.9)1.024 (0.21–3.18)1.731 (1.072–2.515)
 p-value0.5350.9150.151<0.0001
180-day218
 Survivors192155.6 (89.8–287.2)11.75 (8.4–16.4)0.373 (0.085–3.63)0.838 (0.578–1.139)
 Deaths26228.9 (91.1–287.4)14.7 (8.2–18.7)1.004 (0.13–2.94)1.476 (1.056–2.43)
 p-value0.3910.5190.158<0.0001
1-yr150
 Survivors132144.7 (71.7–253.0)11.65 (8.3–16.4)0.255 (0.076–4.41)0.772 (0.50–1.03)
 Deaths18251.9 (181.0–323.3)16.1 (10.5–21.9)1.134 (0.429–6.68)1.238 (1.044–2.471)
 p-value0.0300.0600.069<0.0001
  • Data are presented as median (interquartile range), unless otherwise stated. CRP: C-reactive protein; WBC: white blood cell; PCT: procalcitonin; MR: midregional; proADM: proadrenomedullin. Bonferroni correction was applied (p≤0.003125). Bold indicates statistically significant p-values.