Group | ||||
a | A | R | C | |
Subjects | 7 | 6 | 14 | 11 |
Dust mite-allergic rhinitis | Yes | Yes | Yes | No |
Asthma | Controlled | Uncontrolled | No | No |
Age yrs | 11.5±3.2 | 9.1±0.6 | 11.3±2.8 | 11.5±3.1 |
Males/females | 2/5 | 4/2 | 7/7 | 7/4 |
Epithelial cells % | 85.8±10.4 | 86.5±6.5 | 86.9±8.7 | 86.9±8.5 |
PMNs % | 6.9±6.1 | 5±3.2 | 7.2±7.8 | 6.8±6.1 |
Lymphocytes % | 7.3±10.7 | 8.4±6 | 5.5±7.3 | 6.3±5.6 |
FEV1 | 97.6±13.2 | 78.2±7.7# | 99±9.4 | NA |
FEV1/FVC | 89.3±5.7 | 76.5±3.2# | 90.4±5.2 | NA |
FEF25–75% | 103.6±17.9 | 56.2±9.6# | 107.3±18.2 | NA |
Data are presented as n or mean±sd, unless otherwise stated. Statistical comparisons were performed in allergic (groups a, A and R) versus healthy control subjects (group C) and in uncontrolled (group A) versus controlled (group a) asthmatics using unpaired t-tests and the Chi-squared test. PMN: polymorphonuclear cell; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF25–75%: forced expiratory flow at 25–75% of FVC; NA: not available. #: p<0.005 for group A versus group a by unpaired t-test.