Table 5– Adjusted risk ratios# for infections and persistent wheeze (n=30) at 10 yrs in relation to age of sensitisation
CharacteristicAtopic by 2 yrsp-valueAtopic after 2 yrsp-value
Subjects n6922
Whole population regardless of ARI history2.35 (1.13–4.90)0.0221.22 (0.522.86)0.652
Infections in first year
 Any febrile infections2.29 (1.20–4.40)0.0122.12 (0.83–5.38)0.115
 Any febrile URI1.11 (0.50–2.49)0.7952.58 (1.04–6.43)0.041
 Any LRI with fever3.51 (1.83–6.70)<0.0011.13 (0.17–7.63)0.903
 Any LRI without fever2.11 (1.11–3.99)0.0221.44 (0.52–3.99)0.481
 Any wheezy or febrile LRI2.64 (1.39–5.02)0.0030.67 (0.10–4.54)0.685
 Any wheezy LRI1.60 (0.73–3.47)0.2381.74 (0.46–6.58)0.412
 Any wheezy LRI with fever2.05 (0.88–4.79)0.0962.31 (0.32–16.73)0.406
 Any wheezy LRI without fever1.81 (0.84–3.86)0.1281.43 (0.24–8.51)0.696
 Any wheezy LRI associated with HRV or RSV2.03 (0.97–4.27)0.0612.38 (0.70–8.11)0.166
 Any wheezy LRI associated with HRV2.03 (0.97–4.27)0.0613.46 (1.01–11.82)0.048
 Any wheezy LRI associated with RSV2.80 (0.93–8.46)0.0680
  • Data are presented as risk ratio (95% CI), unless otherwise stated. ARI: acute respiratory illnesses; URI: upper respiratory illness; LRI: lower respiratory illness; HRV: human rhinoviruses; RSV: respiratory syncytial virus. #: adjusted for sex, breastfeeding, pet ownership, older siblings, second-hand tobacco smoke exposure and daycare attendance. Bold indicates statistical significance.