Table 2– Patient characteristics and statistical significance of the association with polymeric immunoglobulin receptor (pIgR) staining intensity
CharacteristicResultp-value
Sex0.192
 Male113 (65)
 Female62 (35)
Race0.066
 Caucasian162 (93)
 African-American13 (7)
Age at diagnosis yrs66 (58–72)0.041
 ≤6061 (35)0.031
 >60114 (65)
Smoking status
 Current smoker59 (34)0.61
 Ex-smoker104 (60)
 Never-smoker10 (6)
Smoking history pack-yrs50 (30–80)0.086
DL,CO % pred76 (57–96)0.976
FEV1 % pred68 (54–85)0.703
Lung cancer histology<0.0001
 ADC98 (56)
 SCC67 (38)
 Undifferentiated NSCLC10 (6)
Pathological stage0.151
 I102 (58)
 II19 (11)
 III35 (20)
 IV19 (11)
Pathological tumour stage0.460
 T168 (40)
 T263 (37)
 T318 (11)
 T422 (13)
Pathological node stage0.095
 N0132 (78)
 N112 (7)
 N226 (15)
Pathological metastasis stage0.332
 M0156 (89)
 M119 (11)
R/P-free survival yrs
 Median (95% CI)4 (2.6–6.8)0.411
 R/P-free at 3 yrs109 (63)0.580
Overall survival yrs
 Median (95% CI)3 (2.4–4.5)0.484
 Alive at 3 yrs90 (51)0.978
Average pIgR staining score
 0121 (69)
 ≥2041 (23)
 ≥5027 (15)
 ≥10012 (7)
  • Data are presented as n (%) or median (interquartile range), unless otherwise stated. DL,CO: diffusing capacity of the lung for carbon monoxide; % pred: % predicted; FEV1: forced expiratory volume in 1 s; ADC: adenocarcinoma; SCC: squamous cell carcinoma; NSCLC: nonsmall cell lung cancer; R recurrence; P: progression. Bold indicates statistically significant p-values.