PT  - JOURNAL ARTICLE
AU  - Burcu Camcioglu
AU  - Muserrefe Nur Karadalli
AU  - Meral Bosnak Guclu
AU  - Zeynep Aribas
AU  - Gulsah Bargi
AU  - Nurdan Kokturk
AU  - Haluk Turktas
TI  - Respiratory and peripheral muscle strength, functional exercise capacity, dyspnea, fatigue and physical activity in patients with interstitial lung disease
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P4283
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P4283.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P4283.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Background: Interstitial lung disease (ILD) causes muscle weakness, dyspnea and functional limitation. However, studies investigated pulmonary and extrapulmonary characteristics in patients with ILD are limited.Aim: To compare pulmonary functions, respiratory and peripheral muscle strength, functional exercise capacity, fatigue and dyspnea in patients with ILD and healthy subjects and determine physical activity in patients with ILD.Methods: Thirty-five patients (47.14±12.35 years) with ILD and 23 healthy subjects (47.43±7.50 years) were compared. Pulmonary functions were measured. Functional exercise capacity was evaluated using 6-minute walk test (6MWT), respiratory muscle strength (MIP, MEP) using a mouth pressure device, peripheral muscle strength using dynamometer, dyspnea using Modified Medical Research Council (MMRC) dyspnea scale, fatigue using Fatigue Impact Scale (FIS). Physical activity were assessed using a multisensory armband device.Results: Demographics, FEV1/FVC and FVC% were similar in groups (p>0.05). FEV1%, PEF% and FEF25-75%, 6MWT distance, MIP, MEP, peripheral muscle strength were significantly lower; MMRC and FIS scores higher in patients with ILD (p<0.05). All of the patients with ILD were inactive (<3.0 METs) according to daily average METs (1.44±0.29 METs) and 65.2% of the patients with ILD were walking <7.500 steps/day.Conclusions: Patients with ILD were physically inactive and have lower muscle strength, functional exercise capacity, and higher dyspnea and fatigue. Further studies are needed to investigate the effects of pulmonary rehabilitation programs in patients with ILD.