TY - JOUR T1 - Estimation of post-operative forced expiratory volume by functional respiratory imaging JF - European Respiratory Journal JO - Eur Respir J SP - 544 LP - 546 DO - 10.1183/09031936.00168314 VL - 45 IS - 2 AU - Annelies Janssens AU - Wim Vos AU - Cedric Van Holsbeke AU - Paul Van Schil AU - Ellie Oostveen AU - Jan De Backer AU - Laurens Carp AU - Annemie Snoeckx AU - Wilfried De Backer AU - Jan P. van Meerbeeck Y1 - 2015/02/01 UR - http://erj.ersjournals.com/content/45/2/544.abstract N2 - Surgical resection is a potential curative therapy for patients with early-stage non-small cell lung cancer (NSCLC). Comorbid chronic obstructive pulmonary disease (COPD) is frequently present in these patients [1], stressing the importance of an accurate estimation of post-operative (po) forced expiratory volume in 1 s (FEV1) [2]. A predicted poFEV1 (PpoFEV1) must be calculated whenever the pre-operative FEV1 or diffusing capacity for carbon monoxide is <80% predicted [3]. The anatomic segment method (ASM) and perfusion scintigraphy (QS) are often used for this prediction [4, 5]. Both are known to underestimate the poFEV1 in a substantial fraction of patients, resulting in the possible exclusion from resection of a borderline operable patient [6, 7]. This stresses the need for a more precise tool to estimate poFEV1.Initial results indicate that FRI might better predict post-operative FEV1; confirmation in a larger trial is needed http://ow.ly/E395t ER -