TY - JOUR T1 - Pathogenicity of individual rhinovirus species during exacerbations of cystic fibrosis JF - European Respiratory Journal JO - Eur Respir J SP - 1748 LP - 1751 DO - 10.1183/09031936.00229114 VL - 45 IS - 6 AU - Amna Shah AU - Michael Connelly AU - Paul Whitaker AU - Chloe McIntyre AU - Christine Etherington AU - Miles Denton AU - Anthony Hale AU - Heli Harvala AU - Peter Simmonds AU - Daniel G. Peckham Y1 - 2015/06/01 UR - http://erj.ersjournals.com/content/45/6/1748.abstract N2 - Pulmonary exacerbations in patients with cystic fibrosis (CF) accelerate deterioration of lung function and cause increased morbidity and mortality [1]. Viruses have been identified in up to 60% of CF related pulmonary exacerbations with a higher prevalence in children [2–5]. Flight et al. [4] identified viruses in 40% of exacerbations in adult patients with CF; viral PCR was performed on nasal, throat, and sputum specimens. We routinely undertake viral throat swabs in all adult patients receiving intravenous antibiotics as part of prospective clinical surveillance, with data automatically uploaded to the electronic patient record (EPR). Patients with self-limiting exacerbations are not screened. In our selected cohort, viral PCR was positive in 9.2% of cases and a positive result is associated with longer duration of treatment, increased inflammatory response, and less recovery of lung volumes [3]. Rhinovirus associated pulmonary exacerbations: no differences in clinical outcomes between individual species http://ow.ly/KJatw ER -