PT  - JOURNAL ARTICLE
AU  - Santiago Juarros Martínez
AU  - Enrique Macías Fernandez
AU  - María Villaverde de Lucas
AU  - Milagros del Olmo Chiches
AU  - Isabel Muñoz Diez
AU  - Mari Fe Muñoz Moreno
AU  - David Vielba Dueñas
AU  - Agueda Herrero Pérez
AU  - Vicente Roig Figueroa
AU  - Isabel Ramos Cancelo
AU  - Carlos Disdier Vicente
TI  - Late-breaking abstract: Adaptive servo-ventilation in central sleep apnea. Ambulatory nocturnal pulse oximetry, a simplified method for monitoring outpatient?
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P2279
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P2279.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P2279.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Background: Adaptive servo-ventilation (ASV) is an effective therapy for patients with hyperventilation-related central sleep apnea (CSA). Simplified method, such as ambulatory nocturnal pulse oximetry (NPO), can help in controlling outpatient therapy.Methods: Patients who started ASV therapy in 2012 were analyzed. Basal oximetry parameters (Oxygen Desaturation Index (ODI), CT90) in the time of diagnosis, versus the same parameters by ambulatory NPO after 1 year of therapy were compared.Results: 19 patients. Cardiac causes in 81% (fig 1).Cheyne-Stokes Breathing (CBS) in 52.6%. After 1 year of therapy: Patients with heart disease, ODI decreased from 35.9 ± 12 to 8.6 ± 6.7 (p 0.012). Patients without heart disease, ODI declined from 51.2 ± 34 to 8.6 ± 8.7 (p 0.043). Patients with CBS, ODI decreased from 36.7 ± 11 to 7.7 ± 6.5 (p 0.018). Patients without CBS, ODI reduced from 46.9 ± 31.5 to 9.6 ± 8.4 (p 0.018) and CT90 decreased from 18.4% ± 13.9% to 4.1 ± 5.2% (p 0.046). 36.8% of cases used ASV over 5 hours daily. In these, ODI decreased from 39.5 ± 12.7 to 7.1 ± 5.3 (p 0.028).Conclusions: ASV to treat CSA, after 1 year, produces significant improvement in ODI in all patients, regardless of cause, with or without associated CBS. Good compliant patients show significant improvement in ODI. Ambulatory NPO can be useful for control, during ambulatory monitoring of these patients.