TY - JOUR T1 - Impact of COPD in patients with coronary heart disease submitted to coronary heart bypass graft JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - 2941 AU - Filipe Leite AU - Pedro Antunes AU - Manuel Antunes Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/2941.abstract N2 - Introduction: The association between COPD and coronary heart disease (CHD) as long been recognized and is included in most risk models. Still the extent of such association remains mostly unknown.Objectives: To analyze the impact COPD in CHD and in the outcome of coronary heart bypass graft (CABG).Material and Methods: Search the center's database for CABG patients with COPD from January 1st 1990 to December 31st 2013.Results: During this period 10791 patients were submitted to CABG (9327 male/1464 female), 356 with the diagnosis of COPD.Considering CHD risk factors, no difference was found in terms of diabetes or hypertension. There was a difference in the incidence of tobacco (P<0.001). Also significant was the existence of family history, dyslipidemia and obesity. No difference existed in the CCS angina score, but COPD had worse ejection fraction and had more coronary arteries affected per patient.Postoperatively there was no difference in the overall mortality, nor in the number of cardiopulmonary arrests. No difference was found in the number of acute coronary syndromes, in the time of assisted ventilation, inotropes used or the number of reoperations due to haemorrhage.A significant difference existed in the number of neurological complications, arrythmias and acute renal damage. Further the incidence of acute respiratory failure was greater in COPD patients (P<0.01, RR=5.2).Conclusion: COPD patients presented with worse CHD, more risk factors and complications. This warrants a better preoperative optimization, a more careful surgery and postoperative period. Further, a stratification of COPD might reveal significant differences between the groups. ER -