RT Journal Article SR Electronic T1 Characteristics of cough reported by adolescents with different ENT disorders JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P4232 VO 44 IS Suppl 58 A1 Maja Jurca A1 Cristian Dogaru A1 AniƱa Pescatore A1 Ben Spycher A1 Philipp Latzin A1 Erol Gaillard A1 Claudia Kuehni YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P4232.abstract AB IntroductionCough is a frequent symptom in children with upper respiratory tract problems. We do not know whether cough characteristics vary between different ENT (Ear,Nose and Throat) disorders, such as allergic rhinitis, habitual snoring and otitis. This study compares the association of different cough characteristics with these disorders.MethodsIn a population-based cohort in Leicestershire, UK, we analysed self-reported respiratory outcomes in adolescents aged 13-17 years in 2010. We computed symptom scores for allergic rhinitis (0-4), chronic snoring (0-3) and otitis (0-2). We estimated odds ratios (ORs) for cough characteristics (coughing more than peers, night cough, cough of long duration (>3 weeks), cough triggered by aeroallergens and exercise) comparing children with high and low ENT symptom scores using logistic regression.ResultsAmong 2,805 children who replied to the questionnaire, 530 reported a high allergic rhinitis score, 217 had severe snoring and 370 had otitis at least once in the last 12 months. Adjusting for age, sex and ethnicity, all ENT disorders showed significant associations with cough, but the results varied between disorders. Severe allergic rhinitis was most strongly associated with cough triggered by aeroallergens (OR 6.4; 95%CI 5.1-7.9), children with a high snoring score reported mainly coughing more than peers (4.1; 3.0-5.7) and cough of long duration (3.6; 2.6-5.1). Otitis was associated with all cough questions with ORs from 1.6 to 2.1.ConclusionCharacteristics of cough in children vary between different ENT disorders. These results help to distinguish underlying aetiologies of cough in children.Funding: SNF PDFMP3 137033; SNF 32003B-144068; Asthma UK 07/048.