RT Journal Article
SR Electronic
T1 High-dose-rate endobronchial brachytherapy (HD-BQT) in radical or palliative therapy for lung cancer
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P695
VO 44
IS Suppl 58
A1 Cayo Garcia Polo
A1 Mercedes Sanchez Bommatty
A1 Mercedes Merino Sanchez
A1 Aurelio Arnedillo Muñoz
A1 Antonio Hidalgo Muñoz
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P695.abstract
AB HD-BQT is an endoscopic technique indicated for curative or palliative airways neoplasms therapy. Our objective was to evaluate our experience and results with this therapy in our HospitalMethods: Descriptive study of HD-BQT procedures performed in our Hospital between 2008 to 2013. Data recorded include age, sex, symptoms, tumoral stage and histology, location and degree of stenosis, number of sessions, cumulated dose, concurrent therapies, related complications, symptoms or stenosis degree relief and survival after procedureResults: 17 treatments applied to 15 patients with median 62.7 years old (two women). In eight cases the initial symptoms were dyspnea (3), hemoptysis (3) and cough (2). In 15 cases the patients had lung cancer and 2 esophageal cancer. The initial stage was TiS (n=5), IIA (n=1), IIIA (n=3), IIIB (n=3), IV (n=3) and T4N0M0 (esophageal, n=2). The tumor location was RMB (n=8), LMB (n=4), trachea (n=4), LUL (n=2), LRL (n=2) and RUL (n=1). Palliative indication in 10 cases and radical in 7. 69 sessions performed, with 5 Gy dose to 1 cm distance applied in each one. Chemotherapy (n=7), EBR (n=5), cryotherapy (n=1) and argon-plasma coagulation (n=1) were associated. The only relevant complication was pneumothorax in one case (required chest drainage). The symptoms relief was achieved in all the cases, with cough or dyspnea improvement and hemoptysis cessation. The five patients with radical treatments applied are alive and with no evidence or relapse after 58, 54, 50, 38, 22, 21 and 10 months follow-up.Conclusions: In our experience, HD-BQT with radical or palliative purpose achieves good results in terms of symptoms relief, no relapse, tolerance and complications.