@article {Ben AbdelghaffarP3649, author = {Hajer Ben Abdelghaffar and Amani Ben Mansour and Ikbel Khalfallah and Ines Akrout and Hanene Smadhi and Leila Fekih and Hela Hassene and Dorra Greb and Dalinda Belhabib and Mohamed Lamine Megdiche}, title = {The association of lung cancer with active pulmonary tuberculosis}, volume = {44}, number = {Suppl 58}, elocation-id = {P3649}, year = {2014}, publisher = {European Respiratory Society}, abstract = {The association of pulmonary tuberculosis and lung cancer is a rare entity. The diagnosis and management can be difficult. the aim of our study was to assess the particularities of this association. We report a series including 25 cases of pulmonary tuberculosis and lung cancer association hospitalized in our departement seen in 20 years. All our patients are men. the mean age was 63 years. Symptoms are variable. The chest X-ray demonstrates characteristics signs of tuberculosis in 30\% and of cancer in 45\%. CT scan allowed evoking the diagnosis of tuberculos and/or cancer in 50\%. The cancer diagnosis was confirmed by histology; Pieces of endoscopic biopsies in 70\% and pieces of resection in 12\%. Non small cell lung cancer is the most frequent histological types (80\%). the clinical profile of lung cancer, at the time of the diagnosis, remains dominated by the advanced stages (80\%). The mean diagnosis ddelay was 10 days in tuberculosis and 15 days in lung cancer. Antituberculosis chemotherapy was established in 80\% of cases and only 40\% of them were finished their treatment. Antituberculosis and anti-tumor chemotherapy were associated in 8 cases. the median survival was 15 months. It was 25 months in cases of association of antituberculosis and anti-tumor chemotherapy. A serious survey of pulmonary tuberculosis is obligatory, espaecially when the patient is smoker, aged more than 50 years. So that, we can obtain an early diagnosis of the lung cancer and improve prognosis.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/44/Suppl_58/P3649}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }