PT - JOURNAL ARTICLE AU - Atila Akkoclu AU - Kemal Can Tertemiz AU - Aylin Ozgen Alpaydin AU - Volkan Karacam TI - Diagnostic value of PET-CT in pleural diseases DP - 2014 Sep 01 TA - European Respiratory Journal PG - P596 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P596.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P596.full SO - Eur Respir J2014 Sep 01; 44 AB - Introduction:Contribution of pleural needle biopsy for diagnosis of pleural effusion differs according to extensiveness of pleural invasion and disease type. We analysed the diagnostic concordance of pleural needle biopsy and VATS biopsy and the correlation between pleural needle biopsy and pathological SUV uptake in PET-CT.Method: We analysed pleural needle biopsy results of 98 patients retrospectively.Results: 24 patients were diagnosed as malignant, 62 as benign and 12 as non-diagnostic with pleural needle biopsy. VATS was performed in 48 patients. Comprasion between pleural needle biopsy and VATS biopsy is shown.View this table:Table 1PET-CT was performed for 49 patients and 33 have pathological SUV uptake. Malignancy was diagnosed with pleural needle biopsy in 12 patients, 13 with VATS biopsy and one with open lung biopsy in patients with pathological SUV uptake. Seven patients of 16 with non-pathological SUV uptake have malignancy end diagnosis (6 VATS, one pleural needle biopsy). Most of these patients have metastatic tumours other than lungs. (2 lung cancer,3 lymphoma,colon and breast cancer). Malignancy diagnosis with pleural needle biopsy was significantly higher in patients with pathological SUV uptake (p<0,05).Pathological SUV uptake and malignancy diagnosis was statisticaly significantly correlated (p<0,05).Coclusion:Pathological SUV uptake in PET-CT shows malignancy with high rates. Patients suspected from malignancy with non-pathological SUV uptake should be evaluated directly for VATS biopsy due to low diagnostic rates with pleural needle biopsy.