%0 Journal Article %A Elif Yilmazel Ucar %A Omer Araz %A Nafiye Yilmaz %A Metin Akgun %A Mehmet Meral %A Hasan Kaynar %A Leyla Saglam %T Effectiveness of pharmacologic therapies on smoking cessation success: Results of three years of smoking cessation clinic %D 2014 %J European Respiratory Journal %P P4453 %V 44 %N Suppl 58 %X Background:This study aimed to determine the efficacy of several pharmacologic treatments in patients who applied to a smoking cessation clinic.Methods: This retrospective study included 422 patients who presented to our smoking cessation clinic between January 2010 and June 2013, used the pharmacologic treatment as prescribed and completed one-year follow-up period. All patients were assessed using the Fagerstrom Test for Nicotine Dependence (FTND) and received both behavioral therapy and pharmacotherapy. Patients smoking status at one year was learned by telephone interview.Results: The patients were 24.3% female and 75.7% male with a mean age of 38. Patients were divided into three groups: varenicline (166 patients), bupropion (148 patients) and nicotine replacement therapy (108 patients). These groups smoking cessation rates were 32.5%, 23% and 52.8%, respectively, and were statistically significant. The overall success rate was 35%. Further analysis revealed that pharmacologic therapy and gender (p=0.01) were factors that showed statistically significant effects on smoking cessation rates. Males had higher success rates than females. Lack of determination emerged as the most important factor leading to relapse.Conclusion: Nicotine replacement therapy was found to be more effective at promoting abstinence from smoking than other pharmacologic therapies. %U