RT Journal Article
SR Electronic
T1 Cognitive failure in sarcoidosis
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P460
VO 44
IS Suppl 58
A1 Maja Omcikus
A1 Violeta Vucinic
A1 Snezana Filipovic
A1 Jelica Videnovic
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P460.abstract
AB Introduction: Sarcoidosis patients mostly have respiratory symptoms like cough and exertional dypnea, but very often also complain about forgetfulness, memory loss and lack of concentration.Aim: Aim of this study was to investigate is conginitive failure more frequent in sarcoidosis patients compared to healthy controls and which disease factors contribute the most to poor mental performance.Method: This cohort study included 76 sarcoidosis patients.They completed the Cognitive Failure Questionnaire (CFQ), Fatigue Assesment Scale (FAS), Center for Epidemiologic Studies Depression Scale (CESd), The small fiber neuropathy screenig list and pulmonary function testing. The control group consisted of 100 healthy volounteers who completed the CFQ. All the results were obtained using descriptive statistcs methods, tests for difference determination for independent samples and correlation methods.Results: The mean CFQ score was significantly higher in sarcoidosis patients compared to healthy controls. In sarcoidosis group there were 59 females, average age was 49.22±10.9748, 48 patients (pts) had only pulmonary sarcoidosis, while 28pts had one or more extrapulmonary localization of the disease. 64pts had chronic sarcoidosis. Average disease duration was 6.59±5.95 years. There was statistically significant correlation between CFQ scores and disease duration (ρ=0.378, p<0.01), and CFQ and CESd scores (ρ=0.706, p<0.01). There was no difference between patients with pulmonary sarcoidosis compared to patients with multisystem sarcoidosis and no significant difference between patients with and without therapy.Conclusion: Cognitive failure is more often in sarcoidosis patients and correlates with disease duration and depression.