PT  - JOURNAL ARTICLE
AU  - Maria Martino
AU  - Maurizia Lanza
AU  - Maria D'Amato
AU  - Giovanna Caccavo
AU  - Giovanna Calabrese
AU  - Carolina Vitale
AU  - Anna Agnese Stanziola
TI  - Prevalence of chronic ischaemic heart disease in idiopathic pulmonary fibrosis: A single center study
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P4516
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P4516.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P4516.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Background: Idiopathic Pulmonary Fibrosis ( IPF ) is a progressive disease with poor prognosis. Major comorbidities such as cardiovascular diseases have been described.Aim: To investigate the prevalence of chronic ischaemic heart disease ( IHD ) in IPF patients.Methods: 110 consecutive IPF patients (73M; mean age 66±7, range 27-84 years; never smokers 50, former smokers 41; current smokers 19) were prospectively studied. IPF diagnosis was made by current ATS guidelines. The diagnosis of IHD was considered on medical history and coronary angiograms or stress echo test.Results: 63 IPF patients (57.2%) (38M; mean age 65±8, range 45-82 years; 13current smokers, 26 former smokers ) were affected by ischemic heart disease. Pulmonary function test: FEV1 65±18% vs Th; FVC 63±15% vs Th; DLCO 37±13% vs Th and DLCO/VA75±10% vs Th.Conclusions. An increased prevalence of ischaemic heart disease in IPF patients was observed. The high IHD prevalence did not appear to be correlate with the IPF severity. Further studies are needed to investigate the clinical impact of IHD on interstitial lung disease.