RT Journal Article
SR Electronic
T1 Etiological structure from sputum of patients with exacerbation of COPD
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2537
VO 44
IS Suppl 58
A1 Nelya Bisenova
A1 Aigerim Yergalieva
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P2537.abstract
AB Objectives: As is known in 50-60% of cases the reason of chronic obstructive pulmonary disease exacerbations are bacteria. The aim of this study was definition three-year dynamics of resistant strains of Streptococcus pneumoniae, isolated from patients with exacerbation of COPD. Methods: A total of 504 strains isolated from respiratory specimens collected from 271 hospitalized patients diagnosed with exacerbation of COPD at National Scientific Medical Research Center during 2009 – 2013 were included to the study. The identification of isolates and antibiotics susceptibility testing were performed by VITEK 2 (bioMerieux) automated system. Results: The study of etiological structure of sputum showed that Streptococcus pneumoniae and Moraxella catarrhalis were the most common pathogens – 40.4% and 16.0% respectively from the total amount of isolates. Detection of Streptococcus pneumoniae significantly increased from 27.5% in 2009 to 53.5% in 2013 (p<0.001).However, it should be noted reduction of Moraxella catarrhalis from 21.4% to 10.7% (p<0.02) in this period.Also during this period from the sputum of patients were isolated Staphylococcus aureus – 4.5%, Pseudomonas aeruginosa – 2.6%, Streptococcus pyogenes – 4,8%, Candida albicans - 1,6%, Enterococcus spp. – 5.0%. Conclusion: Requires constant microbiological screening of respiratory infections, as it allows establishing the possible change of pathogens, as well as their antibiotic resistance.