RT Journal Article
SR Electronic
T1 Severe infection due to corynebacterium striatum or amycolatum in 6 lung transplanted patients
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3314
VO 44
IS Suppl 58
A1 Anne-Cécile Métivier
A1 Nathalie Grall
A1 Gaelle Dauriat
A1 Olivier Brugière
A1 Hervé Mal
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P3314.abstract
AB Corynebacteria are irregularly shaped gram-positive rods, which are usually commensals of the skin and mucous membranes of humans. With the exception Corynebacterium diphteriae, Corynebacteria are in general considered as a contaminant. During the last few years, an increasing number of publications have reported an association of coryneform bacteria with disease. To the best of our knowledge, serious infections after lung transplantation (LT) have not been reported.Methods : We analyzed retrospectively 9 cases of severe infection, sometimes lethal, in 6 LT recipients, observed at one center.View this table:ResultsIn most of our cases, the strains were amoxicillin resistant. Therefore, the treatment was based on vancomycine or linezolidConclusion : Our results indicate that Corynebacteria sp may be responsible for serious infections in LT recipients. Most cases are amoxicillin resistant and require the use of either vancomycine or linezolid.