RT Journal Article
SR Electronic
T1 Residential radon exposure and risk of lung cancer in never smoking women
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2734
VO 44
IS Suppl 58
A1 María Torres Duran
A1 Alberto Ruano Ravina
A1 Isaura Parente Lamelas
A1 Virginia Leiro Fernandez
A1 José Abal Arca
A1 Carmen Montero Martinez
A1 Carolina Pena ALvarez
A1 Javier Gonzalez Barcala
A1 Olalla Castro Añon
A1 Antonio Golpe Gomez
A1 Cristina Martínez
A1 Maria Jose Mejuto Martí
A1 Alberto Fernandez Villar
A1 Juan Miguel Barros Dios
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P2734.abstract
AB Lung cancer in never smokers (LCINS) is a growing health problem. The WHO estimates that 25% of lung cancer worldwide occurs in never smokers (10-15% in Western countries). LCINS is the 7th largest cause of cancer-related mortality in the world. There is a predominance of women among never smoking lung cancer patients. The most important LCINS risk factor is residential radon exposure. We designed a multicentric hospital-based case-control study to assess the relationship between lung cancer risk and residential radon exposure in never smokers in Galicia (Spain), a radon prone area. Eight hospitals took part in the study. We included 352 never smoking women (140 cases of primary lung cancer and 212 controls). All participants fulfilled the WHO definition of never smoker (<100 cigarettes in lifetime or <1cig/day during 6 moths) and all of them were interviewed by trained personnel with a standardized questionnaire. A radon detector (alpha-track) was placed for 3 months in the participant dwelling. Median age of participant women was 70.5 (interquartilic range: 63-78). Results were analyzed through logistic regression and they are expressed as OR and adjusted by age and environmental tobacco exposure.View this table:Residential radon exposure and risk of lung cancerThese results suggest that never smoking women exposed to residential radon concentrations above 200 Bq/m3 have a close to 3-fold higher risk of lung cancer.