RT Journal Article
SR Electronic
T1 Effects of airborne pollen levels on drug consumption for seasonal allergic rhinoconjunctivitis: A ten-year French study
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3468
VO 44
IS Suppl 58
A1 Denis Caillaud
A1 Sylvie Martin
A1 Clarie Segala
A1 Patricia Vidal
A1 Jérome Lecadet
A1 Paul Rouzaire
A1 Arlette Tridon
A1 Jean-Pierre Besancenot
A1 Michel Thibaudon
A1 Bertrand Evrard
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P3468.abstract
AB Background: The aim of this study was to analyze the short-term relationship between pollen exposure and seasonal allergic rhinitis (SAR) using drug deliveries in Clermont-Ferrand (260,000 inhabitants).Methods: A SAR case was defined as the association of an oral antihistamine and a local antiallergic drug on the same prescription. The relationship between daily changes in pollen concentrations and daily changes in the number of treated SAR cases was analyzed using generalized additive models, taking into account confounding factors.Results: Between 2003-2012, the total yearly number and the yearly median number per day of treated SAR rose, from 7,265 to 11,315 and from 26 to 42. Relative risk of treated SAR (RR [95 CI]) associated with an interquartile increase in pollen concentration increased significantly for Fraxinus 1.01 [1.003-1.03], Betula 1.03 [1.01-1.05], Carpinus 1.02 [1.01-1.03], Platanus 1.04 [1.01-1.09], Poaceae 1.04 [1.038-1.05], Urticaceae whole season 1.02 [1.002-1.04] and Urticaceae first semester 1.17 [1.12-1.23]. Total Platanus and Carpinus pollen counts were low, < 1% of total airborne pollen concentration.Conclusions: The prevalence of treated SAR rose around 55% in 10 years. While confirming the significant increase in treated SAR related to Fraxinus, Betula and Poaceae pollens, this study showed new association between treated SAR and Carpinus and Platanus pollens, although their total pollen counts were< 1% of total pollen counts; it also showed robust correlations with Urticaceae pollens, especially during first semester, suggesting potential allergenic role of Parietaria pollination in this urban mountainous area of central France.