TY - JOUR T1 - Relationship of arterial hypertension and obstructive sleep apnea syndrome JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P2288 AU - Doina Adina Todea AU - Loredana Elena Rosca AU - Andreea Codruta Coman Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P2288.abstract N2 - In recent years, obstructive sleep apnea (OSAS) has been defined as a cardio-metabolic disorder being considered an important risk factor for arterial hypertension. The purpose of this study was to analyze the prediction of arterial hypertension in patients with OSAS.We examined the records of 151 patients reffering to our Sleep Laboratory Center, between february to december 2011, to have nocturnal cardio-respiratory poligraphy for the evaluation of OSAS. Including criteria was cut-off value of <15 events/h according to the Apnea Hypopnea Index (AHI). 105 patients (69.56%) had severe OSAS (>30 events/h); 95 patients (62.90%) had hypertension. Univariate analysis for categorical data has found statistic significance for: ischemic cardiopathy 32 (88.89%) vs 68 (59.13%), p<0.01; snoring 98 (68.53%) vs 2 (25%), p=0.03; restless sleep 79 (71.82%) vs 21 (51.22%), p=0.02.Receiver operating characteristics (ROC) analysis reveals statistic significance for: age (p<0.01, AUC=0.69), neck circumference (p<0.01, AUC=0.67), abdominal circumference (p<0.01, AUC=0.70), BMI (p<0.01, AUC=0.70), glicemia (p=0.03, AUC=0.59), supine AHI position (p=0.03, AUC=0.59), medium O2 saturation (p<0.01, AUC=0.70), oxigen desaturation index (p<0.01, AUC=0.63) and ESS (p=0.03, AUC=0.59). Multivariate analysis on logistic model retains only body mass index, neck circumference and age. Arterial hypertension from OSAS is significantly influenced by body mass index, neck circumference and age. An increase of BMI by 1kg/m2 would entail the risk of hypertension by 2.4%. An increase of 1 cm neck circumference would entail the risk of hypertension by 0.6%. An increase in age by 10 years would entail the risk of hypertension by 7.8%. ER -