TY - JOUR T1 - The analyzes of intensive care unit mortality in patients with chronic obstructive lung diseases: What are the effect of comorbidities? JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P2067 AU - Zuhal Karakurt AU - Esra Akkutuk Ongel AU - Cuneyt Salturk AU - Huriye Berk Takir AU - Bunyamin Burunsuzoglu AU - Feyza Kargin AU - Gulbanu Horzum AU - Ozlem Mocin AU - Gokay Gungor AU - Nalan Adiguzel AU - Adnan Yilmaz Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P2067.abstract N2 - Aim: Objectives are to determine whether comorbidities and clinical variables are predictive of ICU mortality.Methods:Retrospective, observational cohort study was done in a respiratory ICU during 2008-2012. Previously COPD diagnosed patients who admitted to the ICU with ARF were included. Patients' demographics, comorbidities, body mass index(BMI), ICU admission data, application of noninvasive and invasive MV, cause of ARF, length of ICU and hospital stay and mortality were recorded from the patients file. Patients were grouped according to mortality(survival versus non-survival) and groups were compared by all recorded data.Results: In study 1013 COPD patients(749 male) with mean age 70±10 year were included. Comorbidities of nonsurvival (female/male, 40/131) group were significantly higher than survival (female/male, 224/618) group as follows: arrhythmia (24% vs 11%), hypertension (42% vs 34%), CAD (28% vs 11%), and depression (7% vs 3%) (p<.001, p<.035, p<.001, p<.007 respectively). Logistic regression of mortality risk factors revealed as need of IMV, BMI<20kg/m2, pneumonia, CAD, arrhythmia, hypertension, chronic hypoxia, and higher APACHE II (odds ratio, [confidence interval], p values respectively, 27.7[15.7-49.0],p<.001; 6.6[3.5-412.7],p<.001; 5.1[2.9-8.8],p<.001; 2.9[1.5-5.6],p<.001; 2.7[1.4-5.2],p<.003; 2.6[1.5-4.4],p<.001; 2.2[1.2-3.9],p<.008; 1.1[1.03-1.11],p<.001).Conclusions: ICU mortality predictors are arrhythmia, hypertension and CAD in patients with COPD who admitted to ICU due to ARF. Especially it is known that increased ICU mortality in pneumonia patients with COPD having cardiac comorbidities utilized IMV. ER -