TY - JOUR T1 - Late-breaking abstract: Clinical epidemiology of lung cancer in China: A retrospective study of 4205 patients JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P1048 AU - Lei Li AU - Weimin Li AU - Li Zhang AU - Dan Liu Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P1048.abstract N2 - Introduction:The prevalence of lung adenocarcinoma keeps increasing. However, no large-scale survey has been done incorporating the epidemiologic and clinical characteristics with adenocarcinoma.Objectives: To determine the association between population-based distribution, clinical characteristics and histologic subtypes of lung cancer.Methods: 4205 hospitalized patients with lung cancer in China were enrolled in this study. Histologic subtypes were categorized as squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, large cell carcinoma, small cell carcinoma and others. The prevalence of lung cancer subtypes within age and gender were examined, and their association with primary site, lymph node status, TNM stage, histologic grade and metastasis at diagnosis were determined.Results: 1). Adenocarcinoma was the most common type (52.2%), most of the patients were with IV stage tumors (60.1%), low histologic grade (64.9%) and lymph node metastasis (60.7%) at diagnosis. The most common metastatic organs were bone (19.9%), brain (9.9%), and liver (9.1%). 2).The adenocarcinoma was more prevalent among women>45 years old (76.3%) than those <=45 years old (64.8%), men>45 years old (40.5%) and men<=45 years old (55.8%, P<0.001). 3).Women were more likely to have adenocarcinoma (OR 3.98, 95% CI, 3.45-4.59). Adenocarcinoma often metastasized to brain (OR 1.64, 95% CI, 1.33-2.03) and bone (OR 2.11, 95% CI, 1.80-2.48). 4). Almost all small cell carcinoma tumors were with low histologic grade at diagnosis (98.0%, p<.001), and often metastasized to liver (15.7%, p<0.001).Conclusions: Women>45 years old were more easily to have adenocarcinoma, while men were more easily to have squamous carcinoma. ER -