TY - JOUR T1 - Late-breaking abstract: Effectiveness of individualized self management support for children with asthma in Dutch outpatient clinics, preliminary results of a randomized controlled trial JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P1159 AU - Stephanie van Bragt AU - Lisette van den Bemt AU - Anja Vaessen-Verberne AU - Anne Nieuwenhuis AU - Leonie van Veen AU - Hein Brackel AU - Han Hendriks AU - Peter Merkus AU - Tjard Schermer Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P1159.abstract N2 - Aim: Suboptimal paediatric asthma management leads to uncontrolled asthma and impaired health-related quality of life (HRQL). Aim of this study was to assess whether individualized self-management support (ISM) supplementary to usual care (UC) is able to improve HRQL in a relevant proportion (≥25%) of children with asthma.Methods: We performed a 9-month RCT in five Dutch hospital paediatric outpatient clinics. Nurse-led ISM support was tailored to the needs of each child based on a validated online HRQL tool, individual goal setting and action plan (van Bragt S et al. BMC Pediatr 2012;12:137). Study subjects were children (6-11 yr) diagnosed with asthma. Primary outcome was a 9-months change in Paediatric Asthma-related Quality of Life Questionnaire (PAQLQ) score ≥ 0.5 points. A secondary outcome was change in asthma control as measured with the Childhood Asthma Control Test (C-ACT)≥ 2. Intention-to-treat uncorrected and corrected logistic regression analyses were performed.Results: 93 children (mean age 9.0 yr [SD 1.6], 57 boys) were randomised (ISM n=42; UC n=51). In both groups, a substantial proportion showed ≥ 0.5 points improvement in PAQLQ scores (ISM 52.4%, UC 25.5%). Uncorrected and corrected analyses showed differences in favour of ISM: Odds Ratio (OR) 3.22 (95%CI 1.34; 7.74 p<0.01) and OR 2.55 (95%CI 0.95; 6.87, p=0.06). The difference in C-ACT score (ISM 56.8%, UC 40%) was not significant.Conclusion: Our ISM intervention appeared to be effective in improving asthma-specific HRQL in a relevant proportion of primary school aged children with asthma that are managed in paediatric outpatient clinics. ER -